RELATIVE SENSITIVITY OF UNDIFFERENTIATED AND CYCLIC ADENOSINE 3′,5′-MONOPHOSPHATE–INDUCED DIFFERENTIATED NEUROBLASTOMA CELLS TO CYCLOSPORIN A: POTENTIAL ROLE OF β-AMYLOID AND UBIQUITIN IN NEUROTOXICITY

The immunosuppressive drug cyclosporin A has been shown to be effective in preventing corneal allograft reactions in rabbits when administered by intramuscular injection. However, when used systemically in man, the drug may have potentially serious side effects and a series of experiments has therefore been performed in order to investigate the use of topically applied cyclosporin A in rabbit corneal transplants. Using a single set model of the corneal allograft reaction, two groups of rabbits treated with topically applied cyclosporin A for periods of four and thirteen weeks respectively showed significantly increased graft survival compared with untreated controls (P < 0.001).

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Serial passage of a street rabies virus in mouse neuroblastoma cells resulted in attenuation: Potential role of the additional N-glycosylation of a viral glycoprotein in the reduced pathogenicity of street rabies virus

Virus Research ◽

10.1016/j.virusres.2012.01.002 ◽

2012 ◽

Vol 165 (1) ◽

pp. 34-45 ◽

Cited By ~ 27

Author(s):

Kentaro Yamada ◽

Chun-Ho Park ◽

Kazuko Noguchi ◽

Daisuke Kojima ◽

Tatsuya Kubo ◽

...

Keyword(s):

Rabies Virus ◽

Potential Role ◽

Neuroblastoma Cells ◽

Serial Passage ◽

Viral Glycoprotein ◽

Mouse Neuroblastoma

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Potential role of WSB1 isoforms in growth and survival of neuroblastoma cells

Pediatric Research ◽

10.1038/pr.2014.2 ◽

2014 ◽

Vol 75 (4) ◽

pp. 482-486 ◽

Cited By ~ 4

Author(s):

Keren Shichrur ◽

Galina Feinberg-Gorenshtein ◽

Drorit Luria ◽

Shifra Ash ◽

Isaac Yaniv ◽

...

Keyword(s):

Potential Role ◽

Neuroblastoma Cells ◽

Growth And Survival

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H2O2-mediated Cytotoxicity of Pharmacologic Ascorbate Concentrations to Neuroblastoma Cells: Potential Role of Lactate and Ferritin

Cellular Physiology and Biochemistry ◽

10.1159/000315098 ◽

2010 ◽

Vol 25 (6) ◽

pp. 767-774 ◽

Cited By ~ 37

Author(s):

Beate Deubzer ◽

Florian Mayer ◽

Zyrafete Kuçi ◽

Marena Niewisch ◽

Gisela Merkel ◽

...

Keyword(s):

Potential Role ◽

Neuroblastoma Cells

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Thiopental protects human neuroblastoma cells from apoptotic cell death — Potential role of heat shock protein 70

Life Sciences ◽

10.1016/j.lfs.2015.07.029 ◽

2015 ◽

Vol 139 ◽

pp. 40-45 ◽

Cited By ~ 2

Author(s):

Martin Roesslein ◽

Christian Froehlich ◽

Verena Miltenberger ◽

Felix Ulbrich ◽

Ulrich Goebel ◽

...

Keyword(s):

Cell Death ◽

Heat Shock ◽

Heat Shock Protein ◽

Heat Shock Protein 70 ◽

Potential Role ◽

Apoptotic Cell ◽

Neuroblastoma Cells ◽

Human Neuroblastoma Cells ◽

Human Neuroblastoma

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POPDC proteins and cardiac function

Biochemical Society Transactions ◽

10.1042/bst20190249 ◽

2019 ◽

Vol 47 (5) ◽

pp. 1393-1404 ◽

Cited By ~ 4

Author(s):

Thomas Brand

Keyword(s):

Potential Role ◽

Striated Muscle ◽

Short Review ◽

Effector Proteins ◽

Muscle Disease ◽

Disease Genes ◽

Protein Protein Interaction ◽

Interaction Partners ◽

And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

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